comparison between fluconazole and terbinafine in the treatment of tinea corporis and tinea cruris

نویسندگان

mohammad javad yazdanpanah

ali akbar shamsian

masoud shafiee

mohammad reza hedayati-moghadam

kiarash ghazvini

چکیده

objectives: this study aimed to compare the therapeutic efficacy of terbinafine andfluconazole in terms of mycological cure in the treatment of tinea corporis and tineacruris. method: in this clinical trial, 30 patients with t. corporis and t .cruris wereselected. patients were divided into two groups by random selection. the first group wastreated with fluconazole 150 mg weekly for four weeks and the second group wasadministered terbinafine 250 mg daily for two weeks. the participants were followed uptill the end of the treatment and one month after treatment. results: at the end of thetreatment, 64.3% of the subjects in fluconazole group developed clinical and laboratoryresponses; while the second group developed 75% clinical and 81.3% laboratory cure.one month later, 64.3% in the fluconazole group were cured, while in the other group,87.5% were cured. no patient had any side effect. conclusion: although, no significantdifference was observed between these two groups of patients in clinical and laboratoryaspect, as a result of lower price and easier consumption, it is suggested that fluconazoleis more suitable for treatment of tinea infections.

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Comparison between Fluconazole and Terbinafine in the treatment of Tinea corporis and Tinea cruris

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عنوان ژورنال:
journal of mycology research

ناشر: university of tehran

ISSN 2383-3181

دوره 2

شماره 2 2015

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